In a game against the stingy Arizona Cardinal defense, Peyton Manning threw for a career high 479 yards and 4 TDs. His first TD gave him 500 for his career and he finished the day with 503, just 5 behind Brett Favre's 508. Manning also tied Dan Marino's record for most games with 400+ yards passing at 13
Demaryius Thomas had a career day with 226 yards receiving and Wes Welker set a record for most receptions in the NFL by an undrafted player.
By the way, Denver won the game by a 41-20 score.
Read the story by Jeff Legwold of ESPN here